3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine(CAS: 865186-94-3)

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a pyridine derivative with a chloro and a tetramethyl-1,3,2-dioxaborolane substituent. It is a colorless liquid with a molecular weight of approximately 352.12 and a boiling point around 180°C. This compound is used in organic synthesis, particularly in boronate ester formation and as a boronic acid derivative in various chemical reactions.

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is primarily used in the pharmaceutical and chemical industries for the synthesis of organic compounds. It serves as a key reagent in cross-coupling reactions, particularly in the formation of C-C bonds. The compound is also used in the preparation of boronate esters and as a boronic acid derivative in various chemical processes.

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is generally considered safe when handled with appropriate precautions. It is flammable and should be stored in a cool, dry place away from heat sources and direct sunlight. Protective gloves and goggles should be worn during handling to prevent skin and eye contact. Inhalation of vapors should be avoided, and appropriate ventilation is recommended.

3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine should be stored in a tightly closed container in a cool, dry place. It should be kept away from heat sources, direct sunlight, and moisture. The storage temperature should not exceed 25°C, and the container should be protected from light. It is important to keep the compound away from incompatible materials such as oxidizers and ensure proper ventilation in the storage area.