3-Bromo-2-fluoroaniline(CAS: 58534-95-5)

3-Bromo-2-fluoroaniline is a white crystalline solid with a molecular weight of 171.01 g/mol. It has a melting point of 67-69°C and is only slightly soluble in water. It is reactive due to its aromatic nature and the presence of both a bromine and a fluorine substituent. It is also known to undergo electrophilic aromatic substitution reactions.

3-Bromo-2-fluoroaniline can be synthesized via the bromination of 2-fluoroaniline followed by reaction with a suitable brominating agent like N-bromosuccinimide (NBS) in the presence of a radical initiator. Other methods include direct bromination of the parent compound with hydrogen bromide in an appropriate solvent.

3-Bromo-2-fluoroaniline is used in the pharmaceutical industry for the synthesis of intermediates and in the semiconductor industry for doping agents. It is also utilized in the production of dyes and pigments. Its applications in polymers and sensors are less common but are being explored.

3-Bromo-2-fluoroaniline should be handled in a well-ventilated area or fume hood due to its potential irritant properties. Protective equipment such as gloves, goggles, and a lab coat is essential. Spills should be cleaned up using appropriate absorbent materials and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.