3-Methyl 1-(2-methyl-2-propanyl) 1,3-pyrrolidinedicarboxylate(CAS: 122684-33-7)

3-Methyl 1-(2-methyl-2-propanyl) 1,3-pyrrolidinedicarboxylate is a white crystalline solid with a molecular weight of approximately 260.38 g/mol. It has a low solubility in water but is more soluble in common organic solvents like ethanol and acetone. The compound is known for its moderate reactivity and is susceptible to hydrolysis under basic conditions. It can form soluble salts and esters, and its reactivity makes it useful in organic synthesis and various chemical applications.

3-Methyl 1-(2-methyl-2-propanyl) 1,3-pyrrolidinedicarboxylate is typically synthesized through the condensation of 3-methyl-2-methylpropyl 1,3-pyrrolidinecarboxylate with 3-methyl-1,3-pyrrolidinecarboxylic acid. The reaction is catalyzed by a Lewis acid such as aluminum chloride, and the product is isolated by recrystallization. The process typically yields a product with high purity, making it suitable for further chemical transformations.

3-Methyl 1-(2-methyl-2-propanyl) 1,3-pyrrolidinedicarboxylate is used in a variety of industries due to its chemical properties. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs). Additionally, it finds applications in the production of polymers, sensors, and semiconductors, where its reactivity and stability make it a valuable component.

When handling 3-Methyl 1-(2-methyl-2-propanyl) 1,3-pyrrolidinedicarboxylate, it is crucial to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. Fume hoods should be used during handling to minimize inhalation risks. In case of a spill, it should be cleaned up carefully, and appropriate safety data sheets (SDS) should be consulted for detailed cleanup procedures and emergency response guidelines.