2-Amino-N-(2-bromophenyl)benzamide(CAS: 34489-85-5)

2-Amino-N-(2-bromophenyl)benzamide (CAS: 34489-85-5) is a crystalline compound with a molecular weight of approximately 324.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMSO and DMF. The compound exhibits basic properties due to its amine group and reactive towards electrophiles, particularly in amide and amino functionalities.

2-Amino-N-(2-bromophenyl)benzamide (CAS: 34489-85-5) is commonly synthesized via nucleophilic substitution of a bromobenzene derivative with an anilide, followed by amidation under basic conditions. The reaction typically involves a condensation step using a condensing agent like HOBt and a base like DIPEA, with a yield of around 70-80%.

2-Amino-N-(2-bromophenyl)benzamide (CAS: 34489-85-5) is primarily used in the pharmaceutical industry as an intermediate in drug synthesis. It also finds applications in polymer chemistry, where its properties are utilized in the development of functional materials, and in sensor technology due to its reactivity and chemical stability.

When handling 2-Amino-N-(2-bromophenyl)benzamide (CAS: 34489-85-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Handle in a fume hood to avoid inhalation. Ensure proper ventilation and avoid skin contact. In case of a spill, neutralize with an appropriate solution and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety instructions.