(3-(Naphthalen-1-yl)phenyl)boronic acid(CAS: 881913-20-8)

(3-(Naphthalen-1-yl)phenyl)boronic acid (CAS: 881913-20-8) is a crystalline solid with a molecular weight of approximately 276.27 g/mol. It has low solubility in water but is more soluble in organic solvents like dimethylformamide (DMF). This compound exhibits moderate reactivity, especially under basic conditions. It is often used in Suzuki coupling reactions due to its boronic acid functionality.

(3-(Naphthalen-1-yl)phenyl)boronic acid (CAS: 881913-20-8) can be synthesized through a boronic acid formation reaction. Specifically, the reaction involves the coupling of 1-naphthylboronic acid with 3-phenylboronic acid in the presence of a Lewis acid catalyst such as tin(II) chloride (SnCl2) and a base like sodium carbonate (Na2CO3). The yield is typically around 70-80%, with good selectivity for the desired product.

(3-(Naphthalen-1-yl)phenyl)boronic acid (CAS: 881913-20-8) is predominantly used in the pharmaceutical and polymer industries. It serves as a key reactant in the synthesis of various drugs and also finds application in the production of functional polymers. Additionally, it can be utilized in the development of sensors and semiconductors due to its unique chemical properties.

When handling (3-(Naphthalen-1-yl)phenyl)boronic acid (CAS: 881913-20-8), it is essential to use proper personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from strong acids and bases. In case of a spill, immediately clean up with appropriate absorbents and ensure the area is well-ventilated. Safety data sheets (SDS) should be consulted for detailed handling instructions.