2-chloro-9-methyl-purin-6-amine(CAS: 7013-21-0)

2-Chloro-9-methyl-purin-6-amine (CAS: 7013-21-0) is a white to off-white crystalline solid. It has a molecular weight of approximately 266.04 g/mol. The compound is sparingly soluble in water and more soluble in organic solvents like methanol and ethanol. It demonstrates good stability under normal conditions but is sensitive to strong acids and bases. It does not react readily with common reagents but can undergo nucleophilic substitution reactions.

2-Chloro-9-methyl-purin-6-amine is typically synthesized via the alkylation of 6-amino-9-chloropurine with methyl iodide. This reaction is conducted in the presence of a base such as potassium carbonate. The product undergoes selective substitution, yielding high yield and selectivity. The reaction is monitored by TLC or HPLC to ensure completion and purity.

2-Chloro-9-methyl-purin-6-amine (CAS: 7013-21-0) is primarily used in the pharmaceutical industry for the development of antiviral drugs. It is also explored in sensor technology and as a precursor for the synthesis of other purine derivatives. Its applications in semiconductor materials and polymer science are less common but are areas of ongoing research.

When handling 2-chloro-9-methyl-purin-6-amine (CAS: 7013-21-0), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, use appropriate spill cleanup materials and follow the safety data sheet (SDS) guidelines. Storage should be in a cool, dry place, away from strong acids and bases.