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Nutlin-3(CAS: 548472-68-0)

Nutlin-3
CAS Number

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Basic Information

Molecular Formula
C30H30Cl2N4O4
Molecular Weight
581.5 g/mol

Chemical Identifiers

SMILES
CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
InChIKey
BDUHCSBCVGXTJM-IZLXSDGUSA-N

Database References

MDL Number
MFCD07784509

FAQ

Nutlin-3 (CAS: 548472-68-0) is subject to several regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it is classified as a toxic substance. In the European Union, it falls under REACH regulations, requiring registration for substances above one tonne per year. For food and pharmaceutical applications, FDA and EPA regulations apply, requiring stringent testing and documentation.
Alternatives to Nutlin-3 (CAS: 548472-68-0) in synthesis include analogs such as 6-iodo-3-(4-methylphenyl)-1H-indole-2-carboxylic acid and similar structural isomers. Common alternative reagents used in synthesis include acetyl chloride and other appropriately substituted acids. These alternatives can offer similar biological activities with varying levels of toxicity and efficacy.
The market for Nutlin-3 (CAS: 548472-68-0) is growing in research fields, particularly in cancer therapy and cell cycle regulation studies. Research trends focus on its potential as a potent inhibitor of MDM2-p53 interaction. Market trends show increasing demand from pharmaceutical companies and academic institutions, driven by its promising anticancer properties. However, high costs and stringent testing requirements continue to pose challenges.
Waste containing Nutlin-3 (CAS: 548472-68-0) should be handled in accordance with regulatory guidelines. Waste should be collected in appropriate containers, labeled clearly, and stored under controlled conditions to prevent environmental contamination. For disposal, consulting with a hazardous waste management company is recommended. Incineration is a common method, but ensure it meets local emission standards. Always follow environmental protection precautions and local waste disposal regulations.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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