Compound Q&A

Are there alternatives to Nutlin-3 (CAS: 548472-68-0) in synthesis?

Answer

Nutlin-3
Alternatives to Nutlin-3 (CAS: 548472-68-0) in synthesis include analogs such as 6-iodo-3-(4-methylphenyl)-1H-indole-2-carboxylic acid and similar structural isomers. Common alternative reagents used in synthesis include acetyl chloride and other appropriately substituted acids. These alternatives can offer similar biological activities with varying levels of toxicity and efficacy.

About

English Name Nutlin-3
Molecular Formula C30H30Cl2N4O4
Molecular Weight 581.5 g/mol
SMILES CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
InChIKey BDUHCSBCVGXTJM-IZLXSDGUSA-N
Last Updated: 2025-10-15 11:13

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