Pilocarpine(CAS: 92-13-7)

Pilocarpine (CAS: 92-13-7) is a white to off-white crystalline powder. It has a molecular weight of 247.27 g/mol and a solubility of 2.54 g/mL in water. Pilocarpine is moderately reactive with basic substances and stable under normal storage conditions. It exhibits low volatility and is not flammable.

Pilocarpine (CAS: 92-13-7) is typically synthesized via an aromatic amination process. The primary route involves the amination of 1-(2-hydroxyethyl)-3,4-dihydroxybenzene, followed by conversion to the desired amine. Common catalysts include ammonium acetate or other basic catalysts, and the overall process yields a high purity product with good selectivity.

Pilocarpine (CAS: 92-13-7) is primarily used in the pharmaceutical industry for the treatment of glaucoma and dry eye syndrome. It is also utilized in research for studying muscarinic receptors and ion channels. Some applications in the sensor industry include its use in biosensors for monitoring sweat chloride levels in cystic fibrosis diagnostics.

When handling Pilocarpine (CAS: 92-13-7), safety precautions include the use of personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be handled in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate absorbent materials, and contaminated items should be disposed of according to local regulations. Consult the safety data sheet (SDS) for detailed emergency procedures and storage requirements.