5-Azidopentanoic acid(CAS: 79583-98-5)

5-Azidopentanoic acid (CAS: 79583-98-5) is a crystalline solid with a molecular weight of approximately 160.07 g/mol. It is slightly soluble in water and organic solvents. The compound is highly reactive due to the presence of the azido group, which can undergo nucleophilic substitution reactions. It has a pKa of about 4.6 and is pH-sensitive.

5-Azidopentanoic acid is typically synthesized by the azidation of pentanoic acid. This involves treating pentanoic acid with an excess of sodium azide in the presence of a suitable solvent and a catalyst such as tetrabutylammonium bromide. The reaction is carried out under mild conditions to achieve high selectivity and yield.

5-Azidopentanoic acid (CAS: 79583-98-5) is used in the pharmaceutical industry for the production of azido-containing drugs, in polymer chemistry for the modification of polymers, and in sensor technology for the development of sensitive detection devices. It also finds applications in semiconductor manufacturing for certain purification and modification processes.

When handling 5-Azidopentanoic acid (CAS: 79583-98-5), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a laboratory coat. The substance should be handled in a fume hood due to its reactivity and potential to form toxic gases. Spills should be handled carefully, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.