Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate(CAS: 102-37-4)

Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate (CAS: 102-37-4) is a colorless to light yellow liquid with a molecular weight of approximately 206.18 g/mol. It has a pKa of around 2.5 and is slightly soluble in water. The compound is reactive due to the presence of the unsaturated acrylate group and phenolic hydroxyl groups, making it suitable for various chemical reactions and applications.

Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate (CAS: 102-37-4) is commonly synthesized via the reaction of ethyl acrylate or phenol with 3,4-dihydroxybenzaldehyde or its derivatives. The reaction typically involves a condensation followed by an acylation step, often catalyzed by acidic or basic conditions, yielding a high yield of the desired product with good selectivity.

Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate (CAS: 102-37-4) is utilized in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and in the polymer industry for the modification of materials. It also finds applications in the production of sensors and semiconductors due to its reactive groups.

When handling Ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate (CAS: 102-37-4), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up with caution using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.