3-Nitrocinnamic Acid(CAS: 555-68-0)

3-Nitrocinnamic Acid (CAS: 555-68-0) is a crystalline solid with a molecular weight of approximately 208.09 g/mol. It has a solubility of 2.75 g/100 mL in water and is practically insoluble in ethanol. The compound is moderately reactive, prone to hydrolysis and nitration reactions. It exhibits a melting point of about 221-223°C and a density of 1.59 g/cm³.

3-Nitrocinnamic Acid can be synthesized through the nitration of cinnamic acid. A common method involves the nitration of cinnamic acid with a mixture of concentrated nitric acid and sulfuric acid. The reaction is carried out under cooling to prevent excessive heating, leading to a yield of around 70-80%. The process requires careful handling due to the strong oxidizing nature of the nitric acid and the heat sensitivity of the intermediate products.

3-Nitrocinnamic Acid (CAS: 555-68-0) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for its ability to enhance the properties of polymers. Additionally, it finds applications in sensor technology for selective detection of specific molecules. Its unique chemical properties also make it useful in semiconductor manufacturing for etching and other processes.

When handling 3-Nitrocinnamic Acid (CAS: 555-68-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a laboratory coat. Storage should be in a cool, dry place away from incompatible materials such as alkalis and reducing agents. Always use a fume hood during preparation and disposal. In case of spill, avoid contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures and storage recommendations.