Afatinib Dimaleate(CAS: 850140-73-7)

Afatinib Dimaleate is a pharmaceutical compound with the CAS number 850140-73-7. It is a salt form of afatinib, a small molecule kinase inhibitor used primarily in cancer therapy. Its chemical formula is C28H29N7O6S2·C4H4O4 (for the dimaleate salt), and it is known for its stability and solubility in aqueous solutions. Afatinib Dimaleate is widely used in the treatment of non-small cell lung cancer (NSCLC) and other malignancies due to its ability to target specific protein kinases involved in tumor growth.

Afatinib Dimaleate (CAS: 850140-73-7) is mainly used in cancer treatment, particularly for non-small cell lung cancer (NSCLC) and other solid tumors. It functions as a dual inhibitor of EGFR (epidermal growth factor receptor) and HER2 (human epidermal growth factor receptor 2), which are critical in cell proliferation and survival. This compound is also utilized in research settings for studying kinase inhibition mechanisms and in the development of targeted cancer therapies.

Afatinib Dimaleate (CAS: 850140-73-7) is generally considered safe when used as directed in medical treatment, but it requires proper handling to ensure safety. It has been evaluated for toxicity in various studies and is approved for use in oncology. However, precautions should be taken during storage and handling to avoid exposure to moisture, and protective equipment such as gloves and goggles is recommended for laboratory use to minimize risk.

Afatinib Dimaleate (CAS: 850140-73-7) should be stored in a cool, dry, and dark place, away from moisture and light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) in a tightly sealed container. Proper storage conditions are essential to maintain its stability and potency, ensuring it remains effective for its intended use in pharmaceutical applications.