Compound Q&A

What is Afatinib Dimaleate (CAS: 850140-73-7)?

Answer

Afatinib Dimaleate
Afatinib Dimaleate is a pharmaceutical compound with the CAS number 850140-73-7. It is a salt form of afatinib, a small molecule kinase inhibitor used primarily in cancer therapy. Its chemical formula is C28H29N7O6S2·C4H4O4 (for the dimaleate salt), and it is known for its stability and solubility in aqueous solutions. Afatinib Dimaleate is widely used in the treatment of non-small cell lung cancer (NSCLC) and other malignancies due to its ability to target specific protein kinases involved in tumor growth.

About

English Name Afatinib Dimaleate
Molecular Formula C32H33ClFN5O11
Molecular Weight 718.091 g/mol
SMILES OC(=O)/C=C\C(=O)O.OC(=O)/C=C\C(=O)O.CN(C/C=C/C(=O)Nc1cc2c(ncnc2cc1O[C@@H]1COCC1)Nc1ccc(c(c1)Cl)F)C
InChIKey USNRYVNRPYXCSP-JUGPPOIOSA-N
Last Updated: 2025-08-25 01:08

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