Compound Q&A
What are the main uses of Afatinib Dimaleate (CAS: 850140-73-7)?
Answer
Afatinib Dimaleate (CAS: 850140-73-7) is mainly used in cancer treatment, particularly for non-small cell lung cancer (NSCLC) and other solid tumors. It functions as a dual inhibitor of EGFR (epidermal growth factor receptor) and HER2 (human epidermal growth factor receptor 2), which are critical in cell proliferation and survival. This compound is also utilized in research settings for studying kinase inhibition mechanisms and in the development of targeted cancer therapies.
About
CAS No
850140-73-7
English Name
Afatinib Dimaleate
Molecular Formula
C32H33ClFN5O11
Molecular Weight
718.091 g/mol
SMILES
OC(=O)/C=C\C(=O)O.OC(=O)/C=C\C(=O)O.CN(C/C=C/C(=O)Nc1cc2c(ncnc2cc1O[C@@H]1COCC1)Nc1ccc(c(c1)Cl)F)C
InChIKey
USNRYVNRPYXCSP-JUGPPOIOSA-N
Last Updated: 2025-08-25 01:08
