2-Bromo-5-chloroaniline(CAS: 823-57-4)

2-Bromo-5-chloroaniline (CAS: 823-57-4) is a white or off-white crystalline solid with a molecular weight of approximately 223.01 g/mol. It has a melting point of 77-79°C and is slightly soluble in water. The compound is moderately reactive, particularly in its aromatic ring, and can participate in electrophilic aromatic substitution reactions.

2-Bromo-5-chloroaniline (CAS: 823-57-4) is often synthesized via the coupling of 5-chloroaniline with bromine in the presence of a suitable base such as sodium hydroxide. The reaction is typically conducted in an aqueous medium, and the yield is usually around 70-80%. The use of appropriate catalysts and solvents can improve selectivity and yield.

2-Bromo-5-chloroaniline (CAS: 823-57-4) is primarily used in the pharmaceutical, agricultural, and chemical industries. It serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. Additionally, it is utilized in the development of dyes, pigments, and as a reagent in research and development.

Handling 2-Bromo-5-chloroaniline (CAS: 823-57-4) requires strict safety measures. Wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a well-ventilated area and use a fume hood during operations. In the event of a spill, use appropriate containment and clean up according to the Material Safety Data Sheet (MSDS/SDS) guidelines.