Vapreotide(CAS: 103222-11-3)

Vapreotide (CAS: 103222-11-3) is a cyclic octapeptide with a molecular weight of approximately 1089.3 Da. It is poorly soluble in water but soluble in organic solvents. Vapreotide is not highly reactive under normal conditions but can be sensitive to hydrolysis in aqueous solutions. It crystallizes in a form that is stable under typical laboratory conditions.

Vapreotide (CAS: 103222-11-3) is typically synthesized via solid-phase peptide synthesis (SPPS). Commonly, the peptide is built using Fmoc chemistry with a protected amino acid resin. The synthesis involves stepwise coupling of protected amino acids, removal of the protecting groups, and final deprotection to yield the active peptide. The yield and purity are typically high, with efficient removal of by-products and side-products.

Vapreotide (CAS: 103222-11-3) is primarily used in the pharmaceutical industry. It is approved for the treatment of acromegaly and certain neuroendocrine tumors. While it has applications in research and development, its main commercial use is in the pharmaceutical sector for therapeutic purposes.

When handling Vapreotide (CAS: 103222-11-3), it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. Storage should be in a cool, dry place away from light and humidity. Fume hoods should be used during synthesis or handling to minimize exposure. In case of a spill, it should be cleaned up according to the manufacturer's safety data sheet (SDS). Always refer to the SDS for detailed handling and disposal instructions.