Fmoc-D-Aph(Cbm)-OH(CAS: 324017-22-3)

Fmoc-D-Aph(Cbm)-OH (CAS: 324017-22-3) is a crystalline compound with a molecular weight of approximately 539.4 g/mol. It has a low solubility in water but is soluble in organic solvents such as DMF and DMSO. The compound is known for its reactivity in coupling reactions, particularly in solid-phase peptide synthesis.

Fmoc-D-Aph(Cbm)-OH is synthesized via a multi-step process involving the coupling of D-Aph(Cbm) with Fmoc-Cl under anhydrous conditions. The reaction typically requires a coupling reagent such as HOBt and a base like triethylamine. The yield is usually around 70-80%, with high selectivity for the desired product.

Fmoc-D-Aph(Cbm)-OH (CAS: 324017-22-3) is primarily used in the pharmaceutical industry for the synthesis of peptides and proteins. It is also utilized in the polymer industry for functionalization and in the sensor industry for biosensing applications.

When handling Fmoc-D-Aph(Cbm)-OH (CAS: 324017-22-3), ensure the use of appropriate personal protective equipment (PPE), such as gloves, lab coat, and safety goggles. Handle the compound under a fume hood due to its reactivity. In case of a spill, immediately clean it up using appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal.