1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-proline(CAS: 160347-90-0)

1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-proline has a crystalline form with a molecular weight of approximately 232.31 g/mol. It has a solubility of about 1.3 mg/mL in water. Chemically, it is reactive towards nucleophiles and can undergo esterification and amidation reactions.

1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-proline is synthesized through a multi-step process involving esterification of 2-methyl-2-propanol with D-proline or its derivatives, followed by amidation. Commonly used catalysts include acid or base catalysts, and the reaction typically results in a high yield of over 90%.

1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-proline is primarily used in the pharmaceutical industry for the synthesis of peptide-based drugs and as a precursor in organic synthesis. It also has applications in the polymer industry for developing novel polymers and in the sensing and semiconductor industries for specific applications requiring tailored chemical reactivity.

When handling 1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-oxo-D-proline, it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and proper disposal procedures. Always refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for detailed handling and safety information.