4-[(E)-Benzylideneamino]phenol(CAS: 588-53-4)

4-[(E)-Benzylideneamino]phenol is a white crystalline solid with a molecular weight of approximately 236.25 g/mol. It has a melting point of 132-134°C and is slightly soluble in water. This compound exhibits basic properties due to the amino group and can engage in nucleophilic substitution reactions. It is also known for its potential to undergo hydrolysis and condensation reactions.

4-[(E)-Benzylideneamino]phenol is commonly synthesized via the condensation of benzaldehyde and phenylguanidine in the presence of a catalyst like p-toluenesulfonic acid. The reaction yields a high-quality product with good selectivity and moderate to high yield. This method requires careful control of reaction conditions to achieve optimal results.

4-[(E)-Benzylideneamino]phenol is used in various industries due to its chemical properties. It is employed in the pharmaceutical sector as an intermediate in the synthesis of certain drugs. In the polymer industry, it serves as a stabilizer and catalyst. Additionally, it finds applications in the production of sensors and semiconductors.

When handling 4-[(E)-Benzylideneamino]phenol (CAS: 588-53-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately with proper disposal methods. Always refer to the Safety Data Sheet (SDS) for detailed information on safety measures and emergency procedures.