4,4,4-Trifluoro-1-phenyl-1,3-butanedione(CAS: 326-06-7)

4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7) is a white crystalline solid with a molecular weight of approximately 248.23 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. This compound is chemically stable but reactive towards strong bases and reducing agents.

4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7) can be synthesized via a condensation reaction between 3,3,3-trifluoropropionaldehyde and phenylacetic acid. Commonly used catalysts include acid catalysts like sulfuric acid or aqueous hydrochloric acid. The yield is typically 70-80%, with good selectivity to the desired product.

4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also utilized in the polymer industry, particularly in the production of thermoplastics and elastomers, and in the electronics industry for the fabrication of semiconductors and sensors.

Proper personal protective equipment (PPE) must be worn when handling 4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbent materials and disposed of according to local regulations. The Safety Data Sheet (SDS) provides detailed information on handling and storage procedures.