Compound Q&A

How is 4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7) typically synthesized?

Answer

4,4,4-Trifluoro-1-phenyl-1,3-butanedione
4,4,4-Trifluoro-1-phenyl-1,3-butanedione (CAS: 326-06-7) can be synthesized via a condensation reaction between 3,3,3-trifluoropropionaldehyde and phenylacetic acid. Commonly used catalysts include acid catalysts like sulfuric acid or aqueous hydrochloric acid. The yield is typically 70-80%, with good selectivity to the desired product.

About

CAS No 326-06-7
English Name 4,4,4-Trifluoro-1-phenyl-1,3-butanedione
Molecular Formula C10H7F3O2
Molecular Weight 216.16 g/mol
SMILES C1=CC=C(C=C1)C(=O)CC(=O)C(F)(F)F
InChIKey VVXLFFIFNVKFBD-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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