Methyl 4-oxopentanoate(CAS: 624-45-3)

Methyl 4-oxopentanoate (CAS: 624-45-3) is a colorless to light yellow liquid with a molecular weight of 124.16 g/mol. It has a high solubility in ethanol and acetone but is insoluble in water. This compound is moderately reactive, particularly with bases and reducing agents. It forms crystalline solids at temperatures below -10°C and exhibits good reactivity in esterification and ester hydrolysis reactions.

Methyl 4-oxopentanoate (CAS: 624-45-3) can be synthesized by the amidation of 4-oxopentanoic acid with methyl alcohol in the presence of an organic base like triethylamine. The reaction typically proceeds with high yield and good selectivity. Other methods involve direct esterification of 4-oxopentanoic acid with methanol using an acid catalyst such as sulfuric acid.

Methyl 4-oxopentanoate (CAS: 624-45-3) finds applications in the pharmaceutical industry as a precursor in the synthesis of certain drugs and in the polymer industry as a monomer. It is also utilized in the production of sensors and semiconductors, where its chemical properties are leveraged for specific functionalities.

When handling Methyl 4-oxopentanoate (CAS: 624-45-3), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. Store the compound in a well-ventilated area and use a fume hood during operations. In case of a spill, immediately clean up with the appropriate absorbent material and dispose of it according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.