(S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid(CAS: 711017-85-5)

(S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid is a white or off-white crystalline solid. Its molecular weight is approximately 316.43 g/mol. It is sparingly soluble in water but soluble in common organic solvents like methanol and ethanol. This compound is known for its stability and is used in various chemical reactions due to its reactivity. It is a chiral molecule which can be used in pharmaceutical and chemical synthesis applications.

(S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid is typically synthesized via the condensation of tert-butoxycarbonyl amino acid with tetrahydro-2H-pyran-4-yl acetic acid. The reaction is catalyzed by a suitable base, such as triethylamine, and proceeds with high selectivity. The product can be isolated by filtration and purified by recrystallization or column chromatography. The yield is typically around 70-80%. This synthesis method ensures a high-quality product suitable for further chemical transformations.

(S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid finds applications in the pharmaceutical industry as a precursor for the synthesis of various medicinal compounds. It is also used in polymer chemistry for developing novel materials with specific properties. Additionally, this compound can be utilized in the production of sensors and semiconductors, contributing to advancements in technology and electronics.

When handling (S)-2-(tert-Butoxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. This compound should be stored in a cool, dry place to maintain its stability. It is recommended to use a fume hood during handling to minimize exposure to potential irritants. In case of a spill, neutralize the area with an appropriate solvent and clean up carefully. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.