2-(2-Chloroquinazolin-4-yl)-9-phenyl-9H-carbazole(CAS: 1616499-37-6)

2-(2-Chloroquinazolin-4-yl)-9-phenyl-9H-carbazole (CAS: 1616499-37-6) is a crystalline solid with a melting point of approximately 240°C. Its molecular weight is around 432.3 g/mol. The compound is poorly soluble in water but soluble in organic solvents like DMF and DMSO. It shows good thermal stability and exhibits strong fluorescence, which makes it useful in optoelectronic applications. Reaction with nucleophiles is possible but requires careful handling due to its aromatic nature.

2-(2-Chloroquinazolin-4-yl)-9-phenyl-9H-carbazole (CAS: 1616499-37-6) can be synthesized through a multi-step procedure involving the condensation of 4-chloroquinazoline with phenyl carbazone followed by cyclization. The reaction typically uses a mild base like triethylamine and is carried out in a suitable solvent like DMF. The yield is usually around 70-80%, and the product can be isolated by recrystallization from ethanol.

2-(2-Chloroquinazolin-4-yl)-9-phenyl-9H-carbazole (CAS: 1616499-37-6) is primarily used in the pharmaceutical and optoelectronic industries. It serves as a key intermediate in the development of new drugs and is also employed in the production of organic light-emitting diodes (OLEDs) due to its excellent photoluminescent properties. The compound may also find applications in polymer sensing and semiconductor devices.

When handling 2-(2-Chloroquinazolin-4-yl)-9-phenyl-9H-carbazole (CAS: 1616499-37-6), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Fume hood use is recommended during synthesis and handling to minimize inhalation risks. Spills should be cleaned up using absorbent materials and proper waste disposal procedures followed. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and storage.