N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dipicolinamide(CAS: 172138-95-3)

N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dipicolinamide (CAS: 172138-95-3) is a crystalline solid with a molecular weight of approximately 274.24 g/mol. It has a high solubility in organic solvents like DMSO and DMF but is poorly soluble in water. The compound is moderately reactive, with typical amide groups being susceptible to nucleophilic substitution. It is stable under normal conditions but may decompose at elevated temperatures.

N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dipicolinamide is typically synthesized via the condensation of 2,2'-dipicolinic acid with cyclohexanedione, often catalyzed by an acid or base. The reaction involves the formation of a mixed anhydride followed by ring closure. The yield is usually high, and the method can be optimized for better selectivity and purity.

N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dipicolinamide (CAS: 172138-95-3) is used in the pharmaceutical and materials science industries. It serves as a precursor in the development of pharmaceuticals and is also utilized in the synthesis of functional polymers and as a component in sensor applications. Its versatility makes it valuable in both academic and industrial settings.

When handling N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dipicolinamide (CAS: 172138-95-3), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to minimize exposure. Store in a cool, dry place away from direct sunlight and heat sources. In case of spill, follow standard safety procedures and refer to the Material Safety Data Sheet (MSDS) for specific guidelines.