1-Chloro-6-isoquinolinol(CAS: 850197-67-0)

1-Chloro-6-isoquinolinol (CAS: 850197-67-0) has a crystalline form and a molecular weight of approximately 223.6 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is relatively stable but can react with strong bases. Its solubility and reactivity make it useful in various synthetic applications.

1-Chloro-6-isoquinolinol (CAS: 850197-67-0) is typically synthesized via the electrophilic chlorination of 6-isoquinolinol. This process involves the use of chlorine gas in the presence of a suitable catalyst, such as iron chloride. The yield is generally good, with high selectivity for the chlorinated product.

1-Chloro-6-isoquinolinol (CAS: 850197-67-0) finds application in the pharmaceutical industry, where it serves as an intermediate for drug synthesis. It is also used in the chemical industry for the development of dyes and pigments, as well as in the synthesis of certain sensors and semiconductors.

When handling 1-Chloro-6-isoquinolinol (CAS: 850197-67-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. Ensure the substance is handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up with appropriate absorbent materials and in accordance with SDS guidelines. Always refer to the Safety Data Sheet (SDS) for detailed safety information.