(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione(CAS: 5596-17-8)

(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione is a crystalline solid with a molecular weight of approximately 228.26 g/mol. It is poorly soluble in water but soluble in polar organic solvents. The compound is reactive towards nucleophiles and can undergo various transformations such as ring-opening reactions. It has a pKa of about 7.5, indicating its basic nature.

(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione can be synthesized via a multistep process involving a ring-opening reaction of a cyclic amide followed by a hydroxylation step. Common catalysts include transition metals such as palladium and platinum. The reaction typically yields 70-80% of the desired product with high stereoselectivity.

(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also employed in the polymer industry for the development of new materials. Additionally, it has applications in sensors and semiconductors due to its unique chemical properties.

When handling (1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store it in a well-ventilated area and use a fume hood during handling. In the event of a spill, follow standard safety procedures and consult the Material Safety Data Sheet (MSDS) for specific guidelines. Avoid contact with skin and eyes, and ensure proper disposal of waste materials.