Compound Q&A

How is (1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione (CAS: 5596-17-8) typically synthesized?

Answer

(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione
(1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione can be synthesized via a multistep process involving a ring-opening reaction of a cyclic amide followed by a hydroxylation step. Common catalysts include transition metals such as palladium and platinum. The reaction typically yields 70-80% of the desired product with high stereoselectivity.

About

CAS No 5596-17-8
English Name (1R,2S,6R,7S)-4-Hydroxy-10-oxa-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione
Molecular Formula C8H7NO4
Molecular Weight 181.15 g/mol
SMILES C1=CC2C3C(C1O2)C(=O)N(C3=O)O
InChIKey PPVGNPSAUJFBJY-FBXFSONDSA-N
Last Updated: 2025-11-08 00:00

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