2-[(4-Methoxyphenyl)amino]acetohydrazide(CAS: 79476-73-6)

2-[(4-Methoxyphenyl)amino]acetohydrazide is a white crystalline solid with a molecular weight of approximately 240.25 g/mol. It is slightly soluble in water and has good solubility in common organic solvents. This compound is reactive towards nucleophiles and can undergo various functional group transformations. It also displays good stability under normal conditions but may decompose at elevated temperatures or in the presence of strong acids or bases.

2-[(4-Methoxyphenyl)amino]acetohydrazide is typically synthesized via the reaction of 4-methoxyaniline with acetic anhydride followed by hydrazinolysis. The synthesis involves the stepwise addition of acetic anhydride to 4-methoxyaniline, followed by treatment with hydrazine hydrate to form the final product. The reaction is carried out in a solvent such as ethanol, and the product is isolated by filtration and recrystallization.

2-[(4-Methoxyphenyl)amino]acetohydrazide finds applications in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It is also used in the polymer industry for the modification of polymers and in the sensor industry for the development of gas sensors. Additionally, it has applications in the semiconductor industry for the production of certain materials.

When handling 2-[(4-Methoxyphenyl)amino]acetohydrazide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or in a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed. It is recommended to consult the Material Safety Data Sheet (MSDS/SDS) for specific safety guidelines and emergency procedures.