5-Phenyl-1,2-oxazole-3-carbaldehyde(CAS: 59985-82-9)

5-Phenyl-1,2-oxazole-3-carbaldehyde (CAS: 59985-82-9) is a white crystalline solid with a molecular weight of approximately 174.21 g/mol. It has a melting point of 167-168°C and is slightly soluble in water. This compound is reactive towards nucleophiles and electrophiles, making it useful in various synthetic transformations.

5-Phenyl-1,2-oxazole-3-carbaldehyde (CAS: 59985-82-9) can be synthesized by the condensation of phenylacetaldehyde with urea in the presence of a strong base like sodium hydroxide. The reaction yields a high yield (typically >90%) and can be carried out in high selectivity, making it a common method for its preparation.

5-Phenyl-1,2-oxazole-3-carbaldehyde (CAS: 59985-82-9) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, and in the preparation of functional polymers and sensors. It also finds applications in the development of semiconducting materials due to its unique chemical properties.

When handling 5-Phenyl-1,2-oxazole-3-carbaldehyde (CAS: 59985-82-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific disposal procedures.