(3aR,4R,5R,6aS)-5-Hydroxy-4-[(3S)-3-hydroxy-5-phenyl-1-penten-1-yl]hexahydro-2H-cyclopenta[b]furan-2-one(CAS: 41639-74-1)

The compound is a white to off-white solid with a molecular weight of approximately 312.32 g/mol. It has a low water solubility and is soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles and bases. It exhibits good stability under normal conditions but should be stored in a cool, dry place away from direct sunlight.

This compound can be synthesized via a multi-step process involving the formation of a cyclopentene derivative followed by a Diels-Alder reaction and subsequent hydroxylation steps. The key reagents include phenylacetylene, crotonaldehyde, and a suitably activated dicarbonyl compound. The overall yield is moderate, and the reaction conditions are carefully controlled to achieve high selectivity.

This compound is primarily used in the pharmaceutical industry as a precursor to drug synthesis. It also finds applications in the production of certain types of polymers and as a building block in the development of new materials for sensors and semiconductors. Its unique chemical structure makes it a valuable intermediate in various chemical processes.

Proper personal protective equipment (PPE) should be worn when handling this compound, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up promptly and according to the Material Safety Data Sheet (MSDS) guidelines. Storage should be done in a cool, dry place away from direct sunlight, and the compound should be handled with care to avoid skin contact and inhalation.