(2R)-3-(4-bromophenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid(CAS: 79561-82-3)

(2R)-3-(4-bromophenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid is a white crystalline solid with a molecular weight of approximately 341.27 g/mol. It is slightly soluble in water but soluble in organic solvents like DMSO and methanol. It exhibits moderate reactivity, particularly with nucleophiles. This compound is stable under normal conditions but should be stored in a cool, dry place to prevent degradation.

(2R)-3-(4-bromophenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid is usually synthesized via the condensation of 4-bromophenylacetic acid with tert-butoxycarbonyl chloride in the presence of a base such as diisopropylethylamine. The reaction is typically conducted in an organic solvent like dichloromethane or tetrahydrofuran, with high selectivity and yields up to 90%. The product is then purified using column chromatography or recrystallization.

(2R)-3-(4-bromophenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid is primarily used in the pharmaceutical industry as an intermediate for the synthesis of bioactive molecules. It is also relevant in the polymer industry for developing new materials with specific properties, and in the sensor industry for creating sensitive detection devices. Additionally, it may find applications in the semiconductor industry for certain processing steps.

Proper handling of (2R)-3-(4-bromophenyl)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid (CAS: 79561-82-3) requires the use of personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, it should be cleaned up using appropriate absorbent materials and the area should be ventilated. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.