(2-Fluorophenyl)(oxo)acetic acid(CAS: 79477-86-4)

(2-Fluorophenyl)(oxo)acetic acid is a white crystalline solid with a molecular weight of approximately 191.07 g/mol. It has a melting point of around 162-164°C and is slightly soluble in water. The compound is reactive, particularly towards nucleophiles due to the presence of the acetoxy group and the fluoro substituent.

(2-Fluorophenyl)(oxo)acetic acid can be synthesized by the acetylation of 2-fluorophenol. The reaction involves treating 2-fluorophenol with acetic anhydride in the presence of an acid catalyst, such as sulfuric acid, at elevated temperatures. The product mixture is then purified through recrystallization or distillation.

(2-Fluorophenyl)(oxo)acetic acid finds applications in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various fluorinated compounds and can be used in the development of new drugs. Additionally, it may be used in the production of certain polymers and in the preparation of sensors and semiconductors.

When handling (2-Fluorophenyl)(oxo)acetic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation of dust or vapors. Spills should be cleaned up carefully following standard procedures, and the substance should be stored in a cool, dry place away from heat sources and incompatible materials. Refer to the Safety Data Sheet (SDS) for detailed handling and storage information.