(2-Fluoro-6-iodophenyl)boronic acid(CAS: 870777-22-3)

(2-Fluoro-6-iodophenyl)boronic acid is a crystalline compound with a molecular weight of approximately 345.07 g/mol. It has low water solubility and moderate solubility in organic solvents such as ethanol and acetone. This compound shows high reactivity in boronate ester formation and is commonly used in organic synthesis for its stabilizing effects on boronic acids.

(2-Fluoro-6-iodophenyl)boronic acid can be synthesized using a fluoroiodophenol as a starting material, followed by a boronic acid coupling reaction. Common methods involve the use of palladium catalysts and base, with good selectivity and yield. The reaction typically occurs in the presence of anhydrous conditions to avoid decomposition.

(2-Fluoro-6-iodophenyl)boronic acid finds applications in pharmaceuticals for drug synthesis, in polymers for functionalization, and in sensors for reactivity testing. It is also utilized in semiconductor manufacturing for its unique chemical properties, making it a versatile compound across various industries.

When handling (2-Fluoro-6-iodophenyl)boronic acid, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a fume hood to minimize exposure. In case of a spill, it should be handled using appropriate cleanup procedures and materials. Always consult a safety data sheet (SDS) for detailed handling and disposal instructions.