Nickel-catalyzed regioselective hydrogen isotope exchange accelerated by 2-pyridones
Literature Information
Zhi-Jiang Jiang, Erxun Hu, Jian-Fei Bai, Bencan Tang
A nickel-catalyzed hydrogen isotope exchange has been developed with acetone-d6 as the deuterium source. The reaction showed an improved kinetic feature of H/D exchange under the assistance of 2-pyridones, efficiently affording regioselective labeled aryl and alkyl carboxamides.
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