Photocatalytic C(sp3)–H thiolation by a double SH2 strategy using thiosulfonates

Literature Information

Publication Date 2023-11-23
DOI 10.1039/D3CC05149H
Impact Factor 6.222
Authors

Nobukazu Taniguchi, Mamoru Hyodo, Lin-Wei Pan


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Abstract

Site-selective C(sp3)–H thiolation using thiosulfonates has been achieved using the decatungstate anion as a photocatalyst. Using the protocol, a variety of thiolated compounds were synthesized in good yields. The transformation consists of a cascade of double SH2 reactions, HAT and ArS group transfer, and PCET (proton-coupled electron transfer) of the leaving arylsulfonyl radical to arylsulfinic acid thus allowing the catalyst, W10O324−, to be recovered.

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