Artificial nucleotide codons for enzymatic DNA synthesis
Literature Information
Nazarii Sabat, Andreas Stämpfli, Marie Flamme, Steven Hanlon, Serena Bisagni, Filippo Sladojevich, Kurt Püntener, Marcel Hollenstein
Herein, we report the high-yielding solid-phase synthesis of unmodified and chemically modified trinucleotide triphosphates (dN3TPs). These synthetic codons can be used for enzymatic DNA synthesis provided their scaffold is stabilized with phosphorothioate units. Enzymatic synthesis with three rather than one letter nucleotides will be useful to produce xenonucleic acids (XNAs) and for in vitro selection of modified functional nucleic acids.
Related Literature
Ionic liquid modulation of swelling and LCST behavior of N-isopropylacrylamide polymer gels
Simon Gallagher, Andrew Kavanagh, Bartosz Zíołkowski, Larisa Florea, Douglas R. MacFarlane, Kevin Fraser, Dermot Diamond
DOI: 10.1039/C3CP53397B
Atomistic insights into the nanohelix of hydrogenated graphene: formation, characterization and application
Liuyang Zhang, Xianqiao Wang
DOI: 10.1039/C3CP53978D
Determination of volatility of ionic liquids at the nanoscale by means of ultra-fast scanning calorimetry
Mathias Ahrenberg, Marcel Brinckmann, Jürn W. P. Schmelzer, Martin Beck, Christin Schmidt
DOI: 10.1039/C3CP54325K
Graphene/g-C3N4 bilayer: considerable band gap opening and effective band structure engineering
Xinru Li, Ying Dai, Yandong Ma, Shenghao Han, Baibiao Huang
DOI: 10.1039/C3CP54592J
Single bubble perturbation in cavitation proximity of solid glass: hot spot versus distance
Helmuth Möhwald, Kenneth Suslick
DOI: 10.1039/C3CP52850B
Reply to the ‘Comment on “Volume shrinkage of a metal–organic framework host induced by the dispersive attraction of guest gas molecules”’ by F.-X. Coudert, A. H. Fuchs, and A. V. Neimark, Phys. Chem. Chem. Phys.
Jaeyong Joo, Hyungjun Kim, Sang Soo Han
DOI: 10.1039/C3CP54473G
Modeling and simulation of the water gradient within a Nafion membrane
Masoumeh Ozmaian
DOI: 10.1039/C3CP54015D
X-ray absorption spectroscopy and resonant inelastic scattering study of the first lithiation cycle of the Li-ion battery cathode Li2−xMnSiO4
M. Dahbi, T. Gustafsson, K. Edström, D. Newby, K. E. Smith, L.-C. Duda
DOI: 10.1039/C3CP54103G
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry











![1-oxaspiro[4.4]nonan-6-one structure 1-oxaspiro[4.4]nonan-6-one structure](https://static.chemtradehub.com/structs/134/134179-01-4-e051.webp)
![1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure 1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure](https://static.chemtradehub.com/structs/914/914637-08-4-8825.webp)

