Photoinduced reductive Reformatsky reaction of α-haloesters and aldehydes or ketones by cooperative dual-metal catalysis
Literature Information
Qi-Long Chen, Le Mao, Yi-Fan Pan, Heng Cai, Xiao-Ming Zhang, Fu-Min Zhang, Ai-Jun Ma, Jin-Bao Peng, Yong-Qiang Tu
A photoinduced reductive Reformatsky reaction by cooperative dual-metal catalysis is described. This methodology enables the implementation of this venerable reaction in environmentally friendly conditions, obviating the need for a stoichiometric amount of metals. A broad range of synthetically useful β-hydroxy esters can be efficiently prepared in moderate to high yields using this protocol.
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Chemical Communications

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