Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy

Literature Information

Publication Date 2023-11-02
DOI 10.1039/D3CC04166B
Impact Factor 6.222
Authors

Qifei Shen, Kai Gao, Zhiqin Zhao, Anran Gao, Yanzi Xu, Heng Wang, Mingming Zhang, Dongfeng Dang


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Abstract

Multifunctional metallacycles with solid-state emission are highly important in cancer therapy. Here, an aggregation-induced emission (AIE)-active metallacycle of DTPABT-MC-R is developed with efficient emission in the NIR region in the solid state (PLQYs = 4.92%). DTPABT-MC-R-based nanoparticles also display excellent photo-stability, and impressive photosensitive characteristics (ROS efficiency = 10.74%), finally leading to applications in cellular imaging and photodynamic therapy (PDT).

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DOI: 10.1039/D0QO90065F

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