High-resolution NMR spectroscopy for measuring complex samples based on chemical-shift-difference selection

Literature Information

Publication Date 2022-12-02
DOI 10.1039/D2CP04279G
Impact Factor 3.676
Authors

Ziqiao Chen, Xueting Li, Yuqing Huang, Shuohui Cao, Zhong Chen, Yulan Lin


View Original

Abstract

NMR spectroscopy serves as an immensely powerful tool for component assignments and molecular structure elucidations. However, proton NMR spectra are generally trapped with spectral congestion caused by limited frequency differences and complex multiplets. 2D NMR can effectively relieve spectral congestion, but its resolution and acquisition efficiency are restricted by the broad spectral bandwidth. Herein, we introduce an NMR method based on chemical-shift-difference selection by chirp excitation to record high-resolution 2D NMR spectra for extracting coupling correlation networks and multiplet structures, suitable for measurements on complex samples. The performance of the proposed method is illustrated in determining diastereotopic methylene protons, small frequency-difference coupled proton pairs of furanose, pyranose and benzene rings. This study is expected to benefit molecular structure elucidation and composition analysis of complex samples in chemistry, biochemistry and metabonomics.

Related Literature

Submicro-polymer particles bearing imidazoline-2-selenone: dual mode adsorbents with color-sensing for halogens and mercury ions

Jaewon Choi, So Yeon Park, Hye Yun Yang, Hae Jin Kim, Kyuwook Ihm, Jeong Ho Nam, Joung Real Ahn, Seung Uk Son

2011-09-20 Paper

DOI: 10.1039/C1PY00260K

Poly(3,4-ethylenedioxythiophene) on self-assembled alkanethiol monolayers for corrosion protection

Denise Azambuja, José I. Iribarren, Carlos A. Ferreira

2011-08-30 Paper

DOI: 10.1039/C1PY00291K

Nylon 3 synthesized by ring opening polymerization with a metal-free catalyst

Hongjun Yang, Junpeng Zhao, Manqing Yan, Stergios Pispas

2011-10-19 Paper

DOI: 10.1039/C1PY00334H

Improving the blood clearance time of 125I labeled Dex-g-PMAGGCONHTyr by copolymerization

Ruigang Liu, Honglang Kang, Bing Jia

2011-06-02 Paper

DOI: 10.1039/C1PY00168J

Single site metallorganic polymerization catalysis as a method to probe the properties of polyolefins

Claudio De Rosa, Finizia Auriemma

2011-06-09 Review Article

DOI: 10.1039/C1PY00129A

Synthetic methodology effect on the microstructure and thermal properties of poly(n-butyl acrylate-co-methyl methacrylate) synthesized by nitroxide mediated polymerization

Adeline Issoulie, Abdel Khoukh, Ahmed Benaboura, Maud Save, Christophe Derail, Laurent Billon

2011-04-26 Paper

DOI: 10.1039/C1PY00066G

Synthesis and characterization of birch wood xylan succinoylated in 1-n-butyl-3-methylimidazolium chloride

Natanya M. L. Hansen, David Plackett

2011-06-28 Paper

DOI: 10.1039/C1PY00086A

Thermally reactive Thiazolo[5,4-d]thiazole based copolymers for high photochemical stability in polymer solar cells

Martin Helgesen, Morten V. Madsen, Birgitta Andreasen, Thomas Tromholt, Jens W. Andreasen, Frederik C. Krebs

2011-09-21 Paper

DOI: 10.1039/C1PY00323B

Polymerization of 4-vinylpyridine and N,N-dimethylacrylamide using a system without organic initiator

Sijing Xia, Bin Yang, Guangzhao Li, Xiaoqing Zhu, Anning Wang, Jin Zhu

2011-07-27 Paper

DOI: 10.1039/C1PY00223F

You might also like

Compound Q&A

What precautions should be taken when handling 2-Methyl-2-propanyl 5-amino-2-thiophenecarboxylate (CAS: 1498311-57-1)?

When handling 2-Methyl-2-propanyl 5-amino-2-thiophenecarboxylate (CAS: 1498311-5...

1498311-57-12-Methyl-2-propanyl ...
Compound Q&A

What are the physical and chemical properties of 5-Bromo-1,2-dichloro-3-fluorobenzene (CAS: 1000572-93-9)?

5-Bromo-1,2-dichloro-3-fluorobenzene (CAS: 1000572-93-9) is a crystalline solid ...

1000572-93-95-Bromo-1,2-dichloro...
Compound Q&A

How should (2R)-2-Amino-2-(4-bromophenyl)ethanol (CAS: 354153-64-3) be stored?

(2R)-2-Amino-2-(4-bromophenyl)ethanol (CAS: 354153-64-3) should be stored in a c...

354153-64-3(2R)-2-Amino-2-(4-br...
Compound Q&A

What regulatory guidelines apply to Methyl 4-(aminomethyl)tetrahydro-2H-pyran-4-carboxylate hydrochloride (CAS: 362707-24-2)?

Methyl 4-(aminomethyl)tetrahydro-2H-pyran-4-carboxylate hydrochloride (CAS: 3627...

362707-24-2Methyl 4-(aminomethy...
Compound Q&A

What are the main uses of 1,4-dimethyl-1H-pyrazole-5-sulfonyl chloride (CAS: 1174834-52-6)?

1,4-Dimethyl-1H-pyrazole-5-sulfonyl chloride is primarily used as an intermediat...

1174834-52-61,4-dimethyl-1H-pyra...
Compound Q&A

Is Dinaphtho[1,2-b:2',1'-d]furan (CAS: 239-69-0) safe?

Dinaphtho[1,2-b:2',1'-d]furan is generally safe when handled with appropriate pe...

239-69-0Dinaphtho[1,2-b:2',1...
Compound Q&A

What is the market or research trend for 7-Methyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione (CAS: 612-37-3)?

The market for 7-Methyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione (CAS: 612-37-3) i...

612-37-37-Methyl-7,9-dihydro...
Compound Q&A

What are the physical and chemical properties of 2-(4-Chlorophenyl)malonaldehyde (CAS: 205676-17-1)?

2-(4-Chlorophenyl)malonaldehyde (CAS: 205676-17-1) is a colorless or light yello...

205676-17-12-(4-Chlorophenyl)ma...
Compound Q&A

How is 2-Methylchrysene (CAS: 3351-32-4) typically synthesized?

2-Methylchrysene (CAS: 3351-32-4) is typically synthesized via the reaction of c...

3351-32-42-Methylchrysene
Compound Q&A

Is N-(6-aminopyrimidin-4-yl)acetamide (CAS: 89533-23-3) safe?

N-(6-aminopyrimidin-4-yl)acetamide (CAS: 89533-23-3) is generally considered saf...

89533-23-3N-(6-aminopyrimidin-...

Source Journal

Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
CiteScore: 5.5
Self-citation Rate: 10.3%
Articles per Year: 3036

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.