![2,9-Dichloro-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione structure](https://static.chemtradehub.com/structs/308/3089-17-6-750b.webp "2,9-Dichloro-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione structure")
2,9-Dichloro-5,12-dihydroquinolino[2,3-b]acridine-7,14-dione
CAS Number:
3089-17-6
Molecular Formula:
C20H10Cl2N2O2
Sequence-controlled and sequence-defined polypeptoids via the Ugi reaction: synthesis and sequence-driven properties
Literature Information
Publication Date
2021-07-19
DOI
10.1039/D1PY00658D
Impact Factor
5.582
Authors
Yinuo Zhu, Youhua Tao
View Original
Abstract
Polypeptoids are peptidomimetic polymers, and their origin can be traced back to the early 1990s. The facile synthesis of sequence-controlled and sequence-defined polypeptoids still faces many challenges. Very recently, the Ugi reaction has been introduced into polypeptoid chemistry. In this mini review, the recent progress in the application of the Ugi reaction for the synthesis of sequence-controlled polypeptoids is summarized. The influence of the sequence structure on polypeptoid properties is presented. Moreover, the future development of the Ugi reaction for the synthesis of sequence-controlled and sequence-defined polypeptoids is discussed.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
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