Recent advances in nitro-involved radical reactions

Literature Information

Publication Date 2020-07-17
DOI 10.1039/D0QO00563K
Impact Factor 5.281
Authors

Jiapian Huang, Feng Ding, Pornchai Rojsitthisak, Fu-Sheng He


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Abstract

Nitro-containing compounds are important structural moieties in drugs, natural products, and small molecule therapeutics, and are widely used in a variety of organic transformations. During the past decades, these compounds have received considerable attention from the synthetic chemistry community, since they have been successfully applied in the preparation of amines, oximes, alkenes, nitrones and alcohols through the radical-initiated pathway. Additionally, significant progress in the chemistry of nitro radicals has been witnessed, providing efficient and rapid access to nitro-containing compounds as well as isoxazoline derivatives. Recent advances in the radical reactions involving the nitro group and various transformations have been summarized in this review.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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