2-(2-Aminoethyl)-1H-isoindole-1,3(2H)-dione hydrochloride (1:1)
CAS Number:
30250-67-0
Molecular Formula:
C10H11ClN2O2
Graphene oxide: a green oxidant-acid bifunctional carbon material for the synthesis of functionalized isoindolin-1-ones via formal amide insertion and substitution
Literature Information
Publication Date
2020-06-15
DOI
10.1039/D0QO00498G
Impact Factor
5.281
Authors
Xiangjun Peng, Dan Hu, Panpan Huang, Huiwu Liao, Yong Zeng, Qian Liu, Liangxian Liu
View Original
Abstract
A formal amide insertion and substitution reaction for the synthesis of functionalized isoindolin-1-ones was developed on the basis of graphene oxide (GO) as a green and oxidant-acid bifunctional carbon material. A series of N-acylisoindolin-1-ones were synthesized in good to excellent yields directly from benzoisofurans and nitriles in the presence of GO without the need for any additives or metals.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine structure](https://static.chemtradehub.com/structs/201/201484-50-6-c2fc.webp "N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine structure")
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine
CAS Number:
201484-50-6
Molecular Formula:
C30H25NO4
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