Continuous-flow crystallisation in 3D-printed compact devices

Literature Information

Publication Date 2019-07-23
DOI 10.1039/C9RE00188C
Impact Factor 4.239
Authors

Obinna Okafor, Karen Robertson, Ruth Goodridge


View Original

Abstract

A flexible and cost-effective methodology to develop compact flow devices with heat exchange ability is presented here. Additive manufacturing techniques allow the rapid design and manufacture of modular jacketed flow devices, where heat exchange can be modelled and controlled to generate efficient devices for applications in continuous-flow cooling crystallisation. As a proof of concept, the crystallisation of paracetamol has been demonstrated. The manufactured devices are effective in crystallising form II paracetamol employing metacetamol as a co-crystallising agent.

Related Literature

Front cover

Cover

DOI: 10.1039/C2CP90211G

A critical perspective on molecular electronic junctions: there is plenty of room in the middle

Haijun Yan, Adam Johan Bergren

2012-11-21 Perspective

DOI: 10.1039/C2CP43516K

Single-crystal adsorptioncalorimetry and density functional theory of CO chemisorption on fcc Co{110}

Kristine Liao, Vittorio Fiorin, David S. D. Gunn, Stephen J. Jenkins, David A. King

2013-02-13 Paper

DOI: 10.1039/C3CP43836H

Nanopatterning by ion implantation through nanoporous alumina masks

Wei Guan, Ian M. Ross, Umananda M. Bhatta, Jay Ghatak, Nianhua Peng, Beverley J. Inkson, Günter Möbus

2013-02-04 Communication

DOI: 10.1039/C3CP50196E

Bombardment induced ion transport – Part III: Experimental potassium ion conductivities in poly(para-xylylene)

S. Schulze, M. Schäfer, A. Greiner, K.-M. Weitzel

2012-11-23 Paper

DOI: 10.1039/C2CP43144K

Coordination number model to quantify packing morphology of aligned nanowire arrays

Itai Y. Stein, Brian L. Wardle

2013-01-15 Paper

DOI: 10.1039/C3CP43762K

Anchoring sites to the STM tip can explain multiple peaks in single molecule conductance histograms

S. Alexis Paz, Martin E. Zoloff Michoff, Christian F. A. Negre, Jimena A. Olmos-Asar, Marcelo M. Mariscal, Cristián G. Sánchez, Ezequiel P. M. Leiva

2012-11-22 Paper

DOI: 10.1039/C2CP43811A

Thermoelectric power factor optimization in PEDOT:PSS tellurium nanowire hybrid composites

Arun Majumdar, Jeffrey J. Urban

2013-01-31 Paper

DOI: 10.1039/C3CP44558E

You might also like

Compound Q&A

What is 3-Fluoro-2-methylbenzylamine (CAS: 771573-36-5)?

3-Fluoro-2-methylbenzylamine is an organic compound with the CAS number 771573-3...

771573-36-53-Fluoro-2-methylben...
Compound Q&A

Is Tert-butyl 2-(oxetan-3-ylidene)acetate (CAS: 1207175-03-8) safe?

Tert-butyl 2-(oxetan-3-ylidene)acetate is considered safe for its intended uses ...

1207175-03-8Tert-butyl 2-(oxetan...
Compound Q&A

What precautions should be taken when handling 4-Acetyl-2-fluorobenzonitrile (CAS: 214760-18-6)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab co...

214760-18-64-Acetyl-2-fluoroben...
Compound Q&A

How is 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6) typically synthesized?

2-Ethyl-4-methyl-1,3-thiazole is commonly synthesized via the reaction of thiour...

15679-12-62-Ethyl-4-methyl-1,3...
Compound Q&A

How should 5',5''-([2,2'-Bithiophene]-5,5'-diyl)bis(([1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid)) (CAS: 1227780-71-3) be stored?

This compound should be stored in a cool, dry place away from direct sunlight an...

1227780-71-35',5''''-([2,2'-Bith...
Compound Q&A

What regulatory guidelines apply to L-Lysine Acetate Salt (CAS: 52315-92-1)?

L-Lysine Acetate Salt (CAS: 52315-92-1) is subject to various regulatory guideli...

52315-92-1L-LYSINE ACETATE SAL...
Compound Q&A

Is 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) safe?

6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (CAS: 259793-96-9) is generally conside...

259793-96-96-Fluoro-3-hydroxy-2...
Compound Q&A

What are the physical and chemical properties of 1,1'-Sulfonylbis(1H-imidazole) (CAS: 7189-69-7)?

1,1'-Sulfonylbis(1H-imidazole) is a crystalline solid with a molecular weight of...

7189-69-71,1'-Sulfonylbis(1H-...
Compound Q&A

What industries use 4-methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5)?

4-Methyl-7-nitro-1H-indole-3-carbonitrile (CAS: 289483-82-5) is primarily used i...

289483-82-54-methyl-7-nitro-1H-...
Compound Q&A

How should waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) be handled?

Waste containing 5-Bromo-3-indolyl-beta-galactoside (CAS: 97753-82-7) should be ...

97753-82-75-Bromo-3-indolyl-be...

Source Journal

Reaction Chemistry & Engineering

Reaction Chemistry & Engineering
CiteScore: 0
Self-citation Rate: 8.8%
Articles per Year: 284

Reaction Chemistry & Engineering is an interdisciplinary journal reporting cutting-edge research focused on enhancing the understanding and efficiency of reactions. Reaction engineering leverages the interface where fundamental molecular chemistry meets chemical engineering and technology. Challenges in chemistry can be overcome by the application of new technologies, while engineers may find improved solutions for process development from the latest developments in reaction chemistry. Reaction Chemistry & Engineering is a unique forum for researchers whose interests span the broad areas of chemical engineering and chemical sciences to come together in solving problems of importance to wider society. All papers should be written to be approachable by readers across the engineering and chemical sciences. Papers that consider multiple scales, from the laboratory up to and including plant scale, are particularly encouraged.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.