Rhodium(iii)-catalyzed ortho-C–H amidation of 2-arylindazoles with a dioxazolone as an amidating reagent
Literature Information
Payel Ghosh, Sadhanendu Samanta, Alakananda Hajra
A simple and efficient method for the directed amidation of a wide range of 2-arylindazoles has been established for the first time through a rhodium-catalyzed C–H activation reaction with alkyl, aryl and heteroaryl dioxazolones. A series of N-(2-(2H-indazol-2-yl)phenyl)acetamide derivatives were synthesized in excellent yields. A mechanistic study was conducted to describe C–H bond cleavage which is likely to be involved in the rate determining step.
Recommended Journals

Current Opinion in Colloid & Interface Science

Russian Journal of Coordination Chemistry

Organic Process Research & Development

Journal of Natural Medicines

Journal of Saudi Chemical Society

Russian Journal of Bioorganic Chemistry

Russian Chemical Bulletin

Russian Journal of Organic Chemistry

Russian Journal of General Chemistry

Nature Medicine
Related Literature
Modulation of the assembly fashion among metal–organic frameworks for enantioretentive epoxide activation
Jun Guo, Xiaomin Xue, Fangfang Li, Meiting Zhao, Youcong Xing, Yanmin Song, Chang Long, Tingting Zhao, Zhiyong Tang
DOI: 10.1039/D3NH00419H
In situ formation of a ZnS/In interphase for reversible Zn metal anodes at ultrahigh currents and capacities
Chengwu Yang, Pattaraporn Woottapanit, Jin Cao, Yilei Yue, Dongdong Zhang, Jin Yi, Zhiyuan Zeng, Xinyu Zhang, Jiaqian Qin, Yonggang Wang
DOI: 10.1039/D3TA05650C
Development of highly conductive anion exchange membranes based on crosslinked PIM-SEBS with high free volume
DOI: 10.1039/D3TA05044K
Magnetic field-responsive graphene oxide photonic liquids
Yi-Tao Xu, Amanda J. Ackroyd, Arash Momeni, Mohamed Oudah
DOI: 10.1039/D3NH00412K
Two-gap topological superconductor LaB2 with high Tc = 30 K
Chin-Hsuan Chen, Ye-Shun Lan, Angus Huang
DOI: 10.1039/D3NH00249G
Synergistic multi-selective photocatalysis and real-time optical thermometry of CsPbBr3/BiOI/TiO2@PAN flexible nanofibers
Yanyan Li, Edwin Yue Bun Pun
DOI: 10.1039/D3TA04964G
Ultrahigh-quality graphene resonators by liquid-based strain-engineering
Mario Hofmann, Chi-Te Liang, Ya-Ping Hsieh
DOI: 10.1039/D3NH00420A
Enriching 2D transition metal borides via MB XMenes (M = Fe, Co, Ir): Strong correlation and magnetism
Jiawei Tang, Duo Wang, Jing Zhang, Litao Sun, Baisheng Sa, Bobby G. Sumpter, Jingsong Huang, Weiwei Sun
DOI: 10.1039/D3NH00364G
Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production
Zhanpin Zhu, Ruibing Chen
DOI: 10.1039/D3NP00012E
siRNA-loaded DNA nanostructures restore endothelial leakiness
Arun Richard Chandrasekaran
DOI: 10.1039/D3NH90040A
You might also like
What regulatory guidelines apply to 6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1)?
6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1) falls under various...
Are there alternatives to 1-Pyrrolidineethanol, β-methyl-α-phenyl-, (αS,βR) (CAS: 123620-80-4) in synthesis?
While there are no direct alternatives, similar compounds like 1-Pyrrolidineetha...
Is 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) safe?
4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) is ...
How should 2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) be stored?
2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) should be stored in a...
What are the physical and chemical properties of 4,5,6,7-Tetrahydro-1H-indazole hydrochloride (CAS: 18161-11-0)?
4,5,6,7-Tetrahydro-1H-indazole hydrochloride is a white crystalline solid with a...
What is (2R)-1-Methoxy-3-phenyl-2-propanamine (CAS: 59919-07-2)?
(2R)-1-Methoxy-3-phenyl-2-propanamine is a chiral organic compound with the CAS ...
What industries use Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate (CAS: 56649-47-9)?
Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate is used in various industries...
What regulatory guidelines apply to 4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3)?
4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3) falls...
What industries use (S)-3-Amino-5-phenylpentanoic acid hydrochloride (CAS: 331846-97-0)?
(S)-3-Amino-5-phenylpentanoic acid hydrochloride is primarily used in the pharma...
How is 7-methoxy-1-benzothiophene-2-carboxylic acid (CAS: 88791-07-5) typically synthesized?
7-Methoxy-1-benzothiophene-2-carboxylic acid is typically synthesized by reactin...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.




