Facile synthesis of yellow fluorescent carbon dots for highly sensitive sensing of cobalt ions and biological imaging
Literature Information
Min Tian, Yaoming Liu, Yingte Wang, Yong Zhang
Long-wavelength light emission has been garnering extensive attention in terms of strong tissue penetration ability and weak light scattering effects. Herein, nitrogen-doped carbon dots (N-CDs) with bright yellow fluorescence emission at 555 nm are facilely synthesized through hydrothermal-assisted heating of o-phenylenediamine and urea. The as-prepared N-CDs exhibit low cytotoxicity, high biocompatibility, photobleaching resistance, and multiple functional groups. Based on the formation of a stable non-fluorescent ground-state complex, the fluorescence intensity of N-CDs is linearly quenched by Co2+ in the range of 0.1–30 μM and the detection limit is as low as 52 nM. The method has been successfully applied for precise analysis of actual samples. Furthermore, the N-CDs satisfactorily serve as a staining probe for the in vivo bioimaging of zebrafish.
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Analytical Methods

Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development












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