Solvent pulse desorption on-line solid-phase extraction combined with high-performance liquid chromatographic determination of 14 sulfonamides in environmental water samples
Literature Information
Feng-Chun Hsieh, Jia-Lin Wang, Youn-Yuen Shu
In this research study, we developed a convenient method for detecting the residue of sulfonamides in water samples using a manual injection valve, octyl (C8) as the sorbent in a solid-phase extraction column, high-performance liquid chromatography, and a diode array detector. Use of gradient flow for a solvent pulse can prevent the use of a second pump and a switch valve. This reduces the cost of instruments. Under optimal conditions, the limits of detection ranged from 0.54 to 3.67 μg L−1, and most drugs had a good relationship (R2 > 0.995). Moreover, during method validation, relative standard deviations for interday and intraday precision ranging from 0.3% to 12% and from 0.1% to 5.4%, respectively, were observed. This method was used to detect sulfonamide residues in environmental water, and the results indicate that neither of the two rivers we studied contained sulfonamides.
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Analytical Methods

Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development










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