Surface-enhanced Raman spectroscopy (SERS) characterisation of abasic sites in DNA duplexes

Literature Information

Publication Date 2019-11-05
DOI 10.1039/C9AN02040C
Impact Factor 4.616
Authors

Luca Guerrini


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Abstract

In this study, direct surface-enhanced Raman scattering (SERS) spectroscopy is used as an exquisite nano-optical tool for ultrasensitive structural characterisation of abasic sites in DNA. In addition, the conformational discrimination (intra- vs. extra-helical) of the nucleobase opposite to the abasic site was also achieved.

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