Synthesis of chiral seven-membered cyclic sulfonamides through palladium-catalyzed arylation of cyclic imines

Literature Information

Publication Date 2019-03-22
DOI 10.1039/C8QO01323C
Impact Factor 5.281
Authors

Lei Shi, Fan-Jie Meng, Yaming Li


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Abstract

An enantioselective palladium-catalyzed addition of arylboronic acids to seven-membered cyclic N-sulfonyl aldimines and ketimines has been developed, giving the chiral cyclic sulfonamides with excellent yields and up to 99% ee.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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